Pre-formulation Services

Pre-formulation is the essential first step in the development of any pharmaceutical product. At Aizant, we utilize advanced technologies to thoroughly assess and optimize the properties of drug substances. Our pre-formulation services focus on creating a stable, effective, and suitable formulation for development into the final product.

Solid-State Characterization

We apply techniques such as X-Ray Diffraction (pXRD), Differential Scanning Calorimetry (DSC), and Thermogravimetric Analysis (TGA) to determine the physicochemical properties of drug substances, including solubility, polymorphism, and stability.

Solubility and Stability Studies

Through pH-solubility profiling and stability studies, we evaluate the drug’s behavior in various environments to optimize performance in the final dosage form.

Salt Form Selection

Our experts perform salt screening and characterization to identify the most effective and stable salt form of the active pharmaceutical ingredient (API).

Excipient Compatibility
Studies

Aizant conducts excipient compatibility testing to confirm that the drug and excipients interact positively, preventing issues during formulation.

Particle Size & Morphology

Utilizing technologies like Laser Diffraction and Malvern Mastersizer, we assess the size, shape, and distribution of drug particles, essential for bioavailability and manufacturing consistency.

Advanced Equipment Used

We employ cutting-edge technology and specialized equipment in our pre-formulation services to ensure optimal outcomes. Our advanced tools enable precise analysis and in-depth testing, ensuring that every compound meets the highest standards for stability and performance in the early stages of development.

Dynamic Vapor Sorption (DVS)
Fourier-Transform Infrared Spectroscopy (FTIR)
Gas Chromatography (GC)
Atomic Absorption Spectroscopy (AAS)

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Pre-Formulation