Our Competencies
Pre-Formulation Development
Our materials science laboratories are equipped with state of the art characterization tools to profile solid and solution state attributes of different dosage forms in support of reverse-engineering, product development and regulatory filing.
Pre-formulation studies
Instrumentation
Pre-formulation studies
- Solid-form screening
- Salt form selection and characterization
- pH-solubility profiling
- pH-stability profiling
- pKa and partition coefficient determination
- Hygroscopicity evaluation
- Particle size and morphology assessment
- Excipient compatibility studies
- Container-closure compatibility studies
- Elemental analysis
- Extractables and leachables studies
- Powder flow characterization
- Discriminating dissolution method development
- USP Type IV dissolution studies
- Residual solvent analysis
- Surface area analysis
Instrumentation
- Thermogravimetric analysis (TGA)
- Differential scanning calorimetry (DSC)
- Dynamic vapor sorption (DVS)
- Powder x-ray diffraction (pXRD)
- Fourier-transform infrared spectroscopy (FTIR)
- Gas chromatography (GC)
- Gas chromatography/Mass spectrometry (GC/MS)
- Liquid-chromatography-Mass Spectrometry (LC/MS/MS)
- Ion chromatography (IC)
- Malvern Zetasizer
- Malvern Mastersizer
- Atomic Absorption Spectroscopy (AAS)
- Inductively coupled plasma mass spectrometry (ICP-MS)
- Polarized light microscopy (PLM)
- Multi-angle light scattering (MALS)
- Anton Parr Rheometer
